2,3,4,6-Tetra-O-Benzyl-D-Glucopyranose CAS 4132-28-9 Assay >99.0% (HPLC) Voglibose Intermediate

2,3,4,6-Tetra-O-Benzyl-D-Glucopyranose (CAS: 4132-28-9), intermediate of Voglibose (CAS: 83480-29-9).
Voglibose, an alpha-glucosidase inhibitor, is a synthetic compound with potent and enduring therapeutic efficacies against disorders of sensory, motor and autonomic nerve systems due to diabetes mellitus. The drug was approved in Japan in 1994 for the treatment of diabetes, and it is under further investigation by Takeda for the treatment of impaired glucose tolerance. Alpha glucosidase inhibitors are oral anti-diabetic drugs used for diabetes mellitus type 2 that work by preventing the digestion of complex carbohydrates (such asstarch). Complex carbohydrates are normally converted into simple sugars (monosaccharides) which can be absorbed through the intestine. Hence, alpha-glucosidase inhibitors reduce the impact of complex carbohydrates on blood sugar.
Voglibose can inhibit various Alpha glucose glycosides enzyme as maltose enzyme, and different maltose enzyme, and glucose starch starch enzyme and the sucrose enzyme of activity, delay sugar points of Digest and absorption, makes starch decomposition into oligonucleotide sugar as maltose (disaccharide), and malt three sugar and the paste fine (low poly sugar), sucrose decomposition into glucose and fructose of speed slows down, caused intestinal on glucose of absorption slow, to ease meal Hou high blood sugar.